Fc-chimeric Protein:

Fc-chimeric proteins are composed of fragment crystallizable (Fc) domain of an immunoglobulin (Ig) molecule that is directly fused with another peptide of interest (Fig. 1). Over the last decade, pioneering work from our group has introduced several FC-chimeric proteins such as epithelial cadherin (E-cad) and IgG Fc (E-cad-Fc), epidermal growth factor (EGF) and IgG Fc, (EGF-Fc), leukemia inhibitory factor (LIF) and IgG Fc (LIF-Fc), hepatocyte growth factor (HGF) and IgG Fc (HGF-Fc), vascular endothelial growth factor (VEGF) and IgG Fc (VEGF-Fc), neural cadherin (N-cad) and IgG Fc (N-cad-Fc) as novel cell-recognizable biomaterials in stem cell technology. These advance biomaterials have shown tremendous potential for advancing stem cell technology closer to application in regenerative medicine and tissue engineering in multiple ways namely, feeder-cell free ESC culture, simplified and cost-effective culture system for stem cell, directed differentiation of stem cell, and on-site stress-free purification of target cells.

Quick notes:
 Comparatively lower cost
 Highly uniform biomaterial
 Superior quality is achievable
 Hassle-free relevant protocol
 Xenogenic agent free biomaterial
 Applicable for in vitro as well for in vivo