Regenerative medicine field has been proceeding by leaping milestones after milestones following the discovery of iPSC technology. However, the relevant protocols and products are yet to satisfy major issues to be applied clinically. Some of these issues are spanning xeno-free protocols, limitation of desired cell population, purity of desired cell population, 3D-structures, proper functionality of the reconstructed tissue etc. Our lab has been successfully advancing the relevant field towards application as exemplified below:
E-cadherin-Fc supports hepatocyte differentiation.
PV-sugars provide selective matrices for hepatocyte culture.
N-cadherin-Fc promotes neuronal cell differentiation.
VE-cadherin-Fc promotes HUVEC culture.