Stem cell technology:
Stem cells, particularly, iPSCs have become the popular choice for regenerative medicine in recent years. However, several critical issues, for example defined culture condition, bulk culture system, homogeneous culture etc., are limiting the progress of the field. Suitable technology has been sought for years to overcome relevant issues. Our lab has been pioneering on solving some of these factors and advancing the field. Some of the remarkable contributions are as follows:
E-cadherin-Fc chimeric protein that provides defined matrix for stem cell culture.
E-cadherin-Fc matrix provides one-stop non-stressed cell purification method.
LIF-Fc provides long-lasting stemness for stem cell culture without regular replenishment of LIF.